Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients
W. Li, X. Luo, M. S. Poetsch, R. Oertel, K. Nichani, M. Schneider, A. Strano, M. Hasse, R. P. Steiner, L. Cyganek, K. Hettwer, S. Uhlig, K. Simon, K. Guan, M. Schubert
This study investigates the effects of HCQ and AZM on iPSC-derived cardiomyocytes, finding that their combination significantly increases cardiotoxicity and electrophysiological dysfunction.
bioRxiv · Aug 19, 2021 · PreprintPharmacology & Toxicology