Cancer BiologybioRxiv
CREB5 reprograms nuclear interactions to promote resistance to androgen receptor targeting therapies
J. H. Hwang, R. Arafeh, J.-H. Seo…·W. Hahn
This study identifies CREB5 as a key driver of resistance to androgen receptor targeting therapies by reprogramming nuclear interactions and activating TGFβ and Wnt signaling pathways.