A. Tavakkoli

This study shows that sleeve gastrectomy worsens colitis-associated colorectal cancer in mice by altering the gut microbiome, which can independently promote tumor growth.

This study shows that daily administration of LuCI, an oral gut coating agent, leads to weight loss and improved insulin sensitivity in a rat model of diet-induced obesity.

The paper shows that restoring TDCA and valine levels in obese mice mimics the weight loss effects of bariatric surgery.

This study uses CyTOF to analyze organ-specific immune cell changes after sleeve gastrectomy in mice, finding shifts in B cell subsets, increased neutrophils, and M2 macrophage polarization linked to metabolic improvements.

This study identifies CA7S, a gut-restricted TGR5 agonist that improves glucose tolerance in insulin-resistant mice by inducing GLP-1 secretion.

This study shows that sleeve gastrectomy improves glucose utilization and remodels adipose tissue metabolism without causing weight loss in mice.