Cancer BiologyNature CommunicationsPeer-reviewed
Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma
M. A. Vittoria, N. M. Kingston, E. Xia…·N. J. Ganem
This study shows that the Hippo tumor suppressor pathway is activated in growth-arrested melanocytes, preventing melanoma development, and its inactivation allows BRAF-driven melanoma formation.