Author

A. Uner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Cetin· 2 shared M. E. Gedik· 2 shared M. Uner· 2 shared O. Saatci· 2 shared O. Sahin· 2 shared S. Aksoy· 2 shared A. Akyol· 1 shared A. Isik· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

M. Cetin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer

O. Saatci, R. Alam, K.-T. Huynh-Dam, A. Isik, M. Uner, N. Belder, P. G. Ersan, M. Cetin, U. M. Tokat, M. E. Gedik, H. Bal, O. S. Sahin, Y. Riazalhosseini, D. Thieffry, D. Gautheret, , O. Sahin

This study identifies LINC00152 as a driver of tamoxifen resistance in ER+ breast cancer by inhibiting ferroptosis, and shows that targeting LINC00152 restores sensitivity to tamoxifen.

bioRxiv · Nov 5, 2023Cancer Biology

Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer

M. E. Gedik, O. Saatci, N. Oberholtzer, M. Uner, O. Akbulut, M. Cetin, M. Aras, K. Ibis, B. Caliskan, E. Banoglu, S. Wiemann, A. Uner, S. Aksoy, S. Mehrotra, O. Sahin

This study shows that T-DM1 induces immunogenic cell death (ICD) in HER2-positive breast cancer, which is lost in resistance, and that targeting TACC3 restores ICD and enhances T-DM1 response.

bioRxiv · Sep 12, 2023 · PreprintCancer Biology