Author

R. Alam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Akyol· 1 shared A. Chandra· 1 shared A. G. Richter· 1 shared A. Isik· 1 shared A. M. Condliffe· 1 shared A. Uner· 1 shared A.-K. Stark· 1 shared B. Ogretmen· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Akyol

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer

O. Saatci, R. Alam, K.-T. Huynh-Dam, A. Isik, M. Uner, N. Belder, P. G. Ersan, M. Cetin, U. M. Tokat, M. E. Gedik, H. Bal, O. S. Sahin, Y. Riazalhosseini, D. Thieffry, D. Gautheret, , O. Sahin

This study identifies LINC00152 as a driver of tamoxifen resistance in ER+ breast cancer by inhibiting ferroptosis, and shows that targeting LINC00152 restores sensitivity to tamoxifen.

bioRxiv · Nov 5, 2023Cancer Biology

PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner

A.-K. Stark, A. Chandra, K. Chakraborty, R. Alam, V. Carbonaro, J. Clark, S. Sriskantharajah, G. Bradley, A. G. Richter, E. Banham-Hall, M. R. Clatworthy, S. Nejentsev, J. N. Hamblin, E. M. Hessel, A. M. Condliffe, K. Okkenhaug

This study identifies a PI3Kδ-driven B cell subset in the lungs that worsens Streptococcus pneumoniae infection independently of antibodies, and shows that inhibiting PI3Kδ improves survival.

bioRxiv · Mar 18, 2018Immunology