Author

M. E. Gedik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Uner· 2 shared M. Cetin· 2 shared M. Uner· 2 shared O. Saatci· 2 shared O. Sahin· 2 shared S. Aksoy· 2 shared A. Akyol· 1 shared A. Isik· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. Uner

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2 papers

Recent·Most cited

Cancer BiologybioRxivNov 5, 2023

Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer

O. Saatci, R. Alam, K.-T. Huynh-Dam…·O. Sahin

This study identifies LINC00152 as a driver of tamoxifen resistance in ER+ breast cancer by inhibiting ferroptosis, and shows that targeting LINC00152 restores sensitivity to tamoxifen.

DOI 10.1038/s41419-024-06814-3

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 12, 2023

Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer

M. E. Gedik, O. Saatci, N. Oberholtzer…·O. Sahin

This study shows that T-DM1 induces immunogenic cell death (ICD) in HER2-positive breast cancer, which is lost in resistance, and that targeting TACC3 restores ICD and enhances T-DM1 response.

DOI 10.1101/2023.09.12.557273

mouseproteomics

𝕏 PostBluesky