Author
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3 papers
Recent·Most cited
The paper develops a computational method to infer population genetics parameters from genomic sequences, finding widespread selection against deleterious mutations in Drosophila melanogaster.
A. Ballal, C. Laurendon, M. Salmon…·A. V. Morozov
The paper investigates sequence determinants of enzyme activity and specificity in terpene synthases using biochemical and computational methods to model free energy landscapes and epistasis.
W. B. Kion-Crosby, M. Manhart, A. V. Morozov
This paper develops a biophysical population genetics model to explain genome-wide codon usage patterns across 20 organisms, finding that codon bias results from selection against mistranslation and mutational robustness.