The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts
H. Liu, L. Zhai, Y. Liu, D. Lu, A. VanderArk, T. Yang, C. M. Krawczyk
This study shows that KDM5C, an X-linked demethylase, promotes energy metabolism in osteoclasts to regulate female bone mass, offering a new target for osteoporosis treatment in women.
bioRxiv · Feb 23, 2023Cell Biology