Author

C. M. Krawczyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

E. H. Ma· 2 shared H. Guak· 2 shared I. Kaymak· 2 shared K. Lau· 2 shared K. S. Williams· 2 shared L. M. DeCamp· 2 shared L. Zhai· 2 shared R. D. Sheldon· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

E. H. Ma

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8+ T cells

E. H. Ma, M. S. Dahabieh, L. M. DeCamp, I. Kaymak, S. M. Kitchen-Goosen, D. G. Roy, M. J. Verway, R. M. Johnson, B. Samborska, C. A. Scullion, M. Steadman, M. Vos, T. P. Roddy, C. M. Krawczyk, K. S. Williams, , R. G. Jones

This study uses 13C-labeled metabolites to show CD8+ T cells switch from glutamine to acetate metabolism during infection.

bioRxiv · Jun 9, 2023 · PreprintImmunology

The histone lysine demethylase KDM5C fine-tunes gene expression to regulate dendritic cell heterogeneity and function

H. Guak, M. J. Weiland, A. R. VanderArk, L. Zhai, K. Lau, B. Mabvakure, M. Corrado, P. Davidson, S. Compton, L. DeCamp, C. Scullion, R. M. Jones, S. Nowinski, C. M. Krawczyk

This study shows KDM5C regulates dendritic cell (DC) heterogeneity and function by modulating epigenetic programming and subset balance, affecting immune responses to infection.

bioRxiv · May 28, 2023 · PreprintImmunology

The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts

H. Liu, L. Zhai, Y. Liu, D. Lu, A. VanderArk, T. Yang, C. M. Krawczyk

This study shows that KDM5C, an X-linked demethylase, promotes energy metabolism in osteoclasts to regulate female bone mass, offering a new target for osteoporosis treatment in women.

bioRxiv · Feb 23, 2023Cell Biology

Ketolysis is a metabolic driver of CD8+ T cell effector function through histone acetylation

K. M. Luda, S. M. Kitchen-Goosen, E. H. Ma, M. J. Watson, L. R. Duimstra, B. M. Oswald, J. Longo, Z. Fu, Z. Madaj, A. Kupai, B. M. Dickson, I. Kaymak, K. Lau, S. Compton, L. M. DeCamp, , R. G. Jones

This study identifies ketone bodies as essential for CD8+ T cell metabolism and effector function through histone acetylation regulation.

bioRxiv · Aug 26, 2022 · PreprintImmunology

PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression

H. Guak, R. D. Sheldon, I. Beddows, A. Vander Ark, H. Shen, R. Jones, J. St. Pierre, E. Ma, C. M. Krawczyk

This study shows that PGC-1β promotes mitochondrial metabolism and suppresses inflammatory gene expression in dendritic cells.

bioRxiv · May 18, 2022Immunology