AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development for mRNA Delivery
Y. Xu, S. Ma, H. Cui, J. Chen, S. Xu, K. Wang, A. Varley, R. X. Z. Lu, W. Bo, B. Li
AGILE uses deep learning and combinatorial chemistry to rapidly design and evaluate ionizable lipids for mRNA delivery, revealing cell-specific preferences for lipid structures.
bioRxiv · Jun 1, 2023Biochemistry