Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
T. Y. Li, Q. Wang, A. W. Gao…·J. Auwerx
This study shows lysosomes mediate the mitochondrial UPR through mTORC1-dependent ATF4 phosphorylation, essential for mitochondrial redox homeostasis and cell survival under stress.
T. Y. Li, A. W. Gao, X. Li…·J. Auwerx
This paper identifies a lysosomal surveillance response (LySR) that reduces proteotoxicity and extends healthspan in worms and mammalian cells by enhancing protein aggregate clearance.
Y. J. Liu, A. W. Gao, R. L. Smith…·R. H. Houtkooper
This study shows that reducing ech-6 expression in C. elegans mitigates fat-induced premature aging, suggesting a role for ech-6 in metabolic flexibility and longevity.
M. Molenaars, B. V. Schomakers, H. L. Elfrink…·R. H. Houtkooper
This paper introduces a single-sample preparation method for comprehensive metabolomics and lipidomics in C. elegans, enabling semi-quantitative analysis of over 100 polar metabolites and over 1000 apolar metabolites.