Three-Dimensional Bioconjugated Liquid-Like Solid (LLS) Enhance Characterization of Solid Tumor - Chimeric Antigen Receptor T cell Interactions
D. T. Nguyen, R. Liu, E. Ogando-Rivas, A. Pepe, D. Pedro, S. Qdaisat, T. Y. N. Nguyen, J. Lavrador, G. Golde, R. Smolcheck, J. Ligon, L. Jin, H. Tao, A. Webber, S. Phillpot, , W. G. Sawyer
This study uses 3D bioconjugated liquid-like solids to model tumor-immune interactions, showing CAR T cells can infiltrate and kill cancer cells while revealing immune escape mechanisms.
bioRxiv · Feb 17, 2023 · PreprintBioengineering