Author

W. G. Sawyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. T. Nguyen· 3 shared A. Pepe· 2 shared D. Pedro· 2 shared E. J. Sayour· 2 shared E. Ogando-Rivas· 2 shared J. Huang· 2 shared P. Castillo· 2 shared R. Liu· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

D. T. Nguyen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 18, 2023

mRNA challenge predicts brain cancer immunogenicity and response to checkpoint inhibitors

P. Castillo, E. Ogando-Rivas, H. Geffrard…·E. J. Sayour

The paper develops an mRNA vaccine to predict brain tumor response to checkpoint inhibitors by analyzing cytokine release patterns in vitro.

DOI 10.1101/2023.03.18.532056

mousebulk RNA-seq

𝕏 PostBluesky

BioengineeringbioRxivPreprintFeb 17, 2023

Three-Dimensional Bioconjugated Liquid-Like Solid (LLS) Enhance Characterization of Solid Tumor - Chimeric Antigen Receptor T cell Interactions

D. T. Nguyen, R. Liu, E. Ogando-Rivas…·W. G. Sawyer

This study uses 3D bioconjugated liquid-like solids to model tumor-immune interactions, showing CAR T cells can infiltrate and kill cancer cells while revealing immune escape mechanisms.

DOI 10.1101/2023.02.17.529033

mouseproteomics

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MicrobiologybioRxivPreprintJan 20, 2021

In vitro infection of human lung tissue with SARS-CoV-2: Heterogeneity in host defense and therapeutic response

M. A. Schaller, Y. Sharma, Z. Dupee…·B. Mehrad

This paper develops an in vitro model using cryopreserved human lung tissue to study SARS-CoV-2 infection and drug responses, revealing donor-specific heterogeneity in viral susceptibility and treatment outcomes.

DOI 10.1101/2021.01.20.427541

humanexperimental assay

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