A. Wilde

The RRM domain-containing protein Rbp3 interacts with ribosomes and the 3' ends of mRNAs encoding photosynthesis proteins

This paper identifies Rbp3 as an RRM domain protein in Synechocystis that binds mRNAs encoding photosynthesis proteins and localizes near ribosomes.

Genetically encoded reporters of actin filament organization in living cells and tissues

This paper develops genetically encoded fluorescent reporters to quantify actin filament organization in living cells and tissues using fluorescence polarization microscopy.

The role of the 5' sensing function of ribonuclease E in cyanobacteria

This study investigates the role of 5' sensing in RNase E of Synechocystis, identifying cleavage sites and demonstrating its impact on rRNA, tRNA maturation, and plasmid copy number.

Regulation of pSYSA defense plasmid copy number in Synechocystis through RNase E and a highly transcribed asRNA

The paper identifies a regulatory mechanism for pSYSA plasmid copy number in Synechocystis involving RNase E and an antisense RNA, revealing a novel replication system with implications for synthetic biology.

mRNA targeting eliminates the need for the signal recognition particle during membrane protein insertion in bacteria

The paper shows that mRNA targeting can replace the SRP pathway for membrane protein insertion in bacteria, using in vivo and in vitro assays.

Feedback regulation of RNase E during UV-stress response in the cyanobacterium Synechocystis sp. PCC 6803

The paper investigates RNase E feedback regulation in Synechocystis sp. PCC 6803 under UV stress, finding increased enzymatic activity and stabilized rne mRNA via 5' UTR autoregulation.

Development of a highly sensitive luciferase-based reporter system to study two-step protein secretion in cyanobacteria

This study develops a NanoLuc-based reporter system to investigate two-step protein secretion in cyanobacteria, revealing that secretion is independent of type IVa pili.

Green light perception paved the way for the diversification of GAF domain photoreceptors

This study reconstructs ancestral cyanobacteriochrome proteins to show they responded to green and red light, enabling cyanobacteria to adapt to different light environments.

Thermosynechococcus switches the direction of phototaxis by a c-di-GMP dependent process with high spatial resolution

This study shows Thermosynechococcus changes phototaxis direction using c-di-GMP signaling with high spatial resolution.

Transcriptome-wide in vivo mapping of cleavage sites for the compact cyanobacterial ribonuclease E reveals insights into its function and substrate recognition

The paper maps RNase E cleavage sites in Synechocystis sp. PCC 6803 using TIER-seq, revealing cleavage signatures and regulatory roles of RNase E and RNase J.

Two circadian oscillators in one cyanobacterium

The paper identifies a new KaiA homolog, KaiA3, in Synechocystis sp. PCC 6803, which forms a second circadian oscillator alongside the standard KaiB3-KaiC3 system.

PATAN-domain response regulators interact with the Type IV pilus motor to control phototactic orientation in the cyanobacterium Synechocystis sp. PCC 6803

The paper identifies the PATAN domain of PatA-type regulators as the key domain interacting with the Type IV pilus motor to control phototactic orientation in Synechocystis.

Homologs of circadian clock proteins impact the metabolic switch between light and dark growth in the cyanobacterium Synechocystis sp. PCC 6803

This study shows that mutations in circadian clock protein homologs in Synechocystis affect metabolic changes during light-to-dark transitions, with rpaA having a stronger impact on carbon and nitrogen metabolism.

Minor pilin genes are involved in motility and natural competence in Synechocystis sp. PCC 6803

This study identifies distinct roles for minor pilins in Synechocystis sp. PCC 6803, showing PilA5 is essential for natural transformation while PilA9-slr2019 is required for motility.

Synechocystis KaiC3 displays temperature and KaiB dependent ATPase activity and is important for growth in darkness

This study characterizes KaiC3 ATPase activity in Synechocystis, showing temperature dependence and interaction with KaiB proteins, and links it to growth in darkness.