S. Timm

Ileal mucus viscoelastic properties differ in Crohns disease

This study examines ileal mucus viscoelastic properties in Crohn's disease patients and controls, finding significant differences in viscoelasticity and mesh size.

Altered iron-sulfur cluster transfer in Arabidopsis mitochondria reveals lipoyl synthase as a Janus-faced enzyme that generates toxic sulfide

The paper shows that altered iron-sulfur cluster transfer in Arabidopsis mitochondria leads to toxic sulfide release by lipoyl synthase, affecting plant growth and sulfide homeostasis.

Nitrite secretion by cyanobacteria is controlled by the small protein NirP1

This study identifies NirP1 as a regulator of nitrite secretion in cyanobacteria under carbon limitation, revealing its role in coordinating carbon and nitrogen metabolism.

Simultaneous adjustments of major mitochondrial pathways through redox regulation of dihydrolipoamide dehydrogenase (mtLPD1)

The paper shows redox regulation of mtLPD1 modulates photorespiration, TCA-cycle, and BCAA degradation in response to environmental changes.

Pyruvate:ferredoxin oxidoreductase and low abundant ferredoxins support aerobic photomixotrophic growth in cyanobacteria

The paper shows that PFOR supports aerobic photomixotrophic growth in cyanobacteria by utilizing ferredoxin instead of NAD(H), saving Gibbs free energy and decelerating metabolism.

Homologs of circadian clock proteins impact the metabolic switch between light and dark growth in the cyanobacterium Synechocystis sp. PCC 6803

This study shows that mutations in circadian clock protein homologs in Synechocystis affect metabolic changes during light-to-dark transitions, with rpaA having a stronger impact on carbon and nitrogen metabolism.

Phycobilisome breakdown effector NblD is required to maintain the cellular amino acid composition during nitrogen starvation

This study shows that NblD is essential for maintaining amino acid and organic acid pools during nitrogen starvation in cyanobacteria by mediating phycobilisome breakdown.

The novel PII-interacting protein PirA regulates flux into the cyanobacterial ornithine-ammonia cycle

This paper identifies PirA, a novel PII-interacting protein that regulates flux into the cyanobacterial ornithine-ammonia cycle by competing with NAGK for PII binding, thereby affecting arginine synthesis and nitrogen storage.

Non-canonical localization of RubisCO under high light conditions in the toxic cyanobacterium Microcystis aeruginosa PCC7806

This study shows that microcystin affects RubisCO localization and function in Microcystis aeruginosa under high light, leading to changes in metabolic products and potential microbial interactions.