F. Iv

Genetically encoded reporters of actin filament organization in living cells and tissues

This paper develops genetically encoded fluorescent reporters to quantify actin filament organization in living cells and tissues using fluorescence polarization microscopy.

Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

This study shows that human septins form octamer-based filaments that mediate actin-membrane anchoring, as demonstrated through various imaging and biophysical techniques.

Septin-microtubule association requires a MAP-like motif unique to Sept9 isoform 1 embedded into septin octamers

The paper identifies a MAP-like motif in Sept9 isoform 1 that drives septin-microtubule interaction and shows how HNA mutations disrupt this association.

Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

This study isolates recombinant human septin octamers with distinct SEPT9 isoforms and shows they form filament assemblies and bind actin filaments.

Membrane binding controls ordered self-assembly of animal septins

This study shows membrane binding enables fly septins to form ordered filamentous arrays, with C-terminal regions required for stacking.