Author

A. Wutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

G. Di Minin· 2 shared A. Grison· 1 shared A. Monfort· 1 shared C. Qi· 1 shared C.-E. Dumeau· 1 shared I. Vercellino· 1 shared L. A. Jerome-Majewska· 1 shared V. M. Korkhov· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

G. Di Minin

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Author profile →

2 papers

Recent·Most cited

Tmed2 regulates Smoothened trafficking and Hedgehog signalling

G. Di Minin, C.-E. Dumeau, A. Grison, W. Chan, A. Monfort, L. A. Jerome-Majewska, A. Wutz

This study identifies Tmed2 as a regulator of Smoothened trafficking and Hedgehog signaling, showing its role in controlling signaling strength during neural differentiation.

bioRxiv · Apr 20, 2020 · PreprintCell Biology

Structural basis of sterol recognition by human hedgehog receptor PTCH1

C. Qi, G. Di Minin, I. Vercellino, A. Wutz, V. M. Korkhov

This study presents a cryo-EM structure of human PTCH1 bound to a modified hedgehog ligand, revealing sterol interactions and potential translocation pathways.

bioRxiv · Dec 30, 2018Biochemistry