V. M. Korkhov

This study determines the cryo-EM structure of the Duffy antigen receptor bound to CCL7, revealing structural features that explain its unique functional properties and lack of G protein coupling.

The paper presents cryo-EM structures of wild-type and CMT1X mutant connexin 32 gap junction channels and hemichannels, revealing a gating helix defect in disease-associated mutants.

The paper determines the cryo-EM structure of bovine AC8 bound to CaM and Gs, identifies interaction sites, and infers conformational changes in the regulation mechanism.

The paper determines the structure of a human Cx43 gap junction channel in a closed state using cryo-EM, revealing a previously unknown conformation stabilized by a small molecule.

The paper determines the cryo-EM structure of Mycobacterium tuberculosis Cya, revealing its TM domain's role in catalytic activity regulation.

The paper presents cryo-EM structures of AC9 in different states to reveal activator-induced conformational changes essential for its activation.

This study presents the cryo-EM structure of Drosophila Dispatched, revealing its open conformation and unique Hh-binding mode, suggesting a receptor-chaperone role in Hedgehog release.

This study presents a cryo-EM structure of human PTCH1 bound to a modified hedgehog ligand, revealing sterol interactions and potential translocation pathways.