ImmunologyJCI InsightPeer-reviewed
Tertiary lymphoid structures induced by CXCL13-producing CD4+ T cells increase tumor infiltrating CD8+ T cells and B cells in ovarian cancer
M. Ukita, J. Hamanishi, H. Yoshitomi…·M. Mandai
This study shows that CXCL13-producing CD4+ T cells induce tertiary lymphoid structures (TLSs) in ovarian cancer, increasing CD8+ T cell and B cell infiltration and improving patient prognosis.
DOI 10.1172/jci.insight.157215