Author

A. Yee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pathology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Ginsburg· 3 shared C. A. Kretz· 2 shared D. R. Siemieniak· 2 shared L. M. Haynes· 2 shared Z. M. Huttinger· 2 shared B. Halloran· 1 shared C. Ren· 1 shared D. A. Lawrence· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

D. Ginsburg

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Platelet Activating Factor Activity Modulates Hyperoxic Neonatal Lung Injury Severity

A. Yee, J. Kandasamy, N. Ambalavanan, C. Ren, B. Halloran, N. Olave, T. Nicola, T. Jilling

This study investigates the role of platelet activating factor (PAF) signaling in hyperoxic neonatal lung injury and BPD by comparing WT and PAF receptor knockout mice.

bioRxiv · Mar 14, 2023 · PreprintPathology

Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability

L. M. Haynes, Z. M. Huttinger, A. Yee, C. A. Kretz, D. R. Siemieniak, D. A. Lawrence, D. Ginsburg

The paper analyzes PAI-1 variants to identify mutations that increase functional stability and inhibitory activity, and develops a method to measure functional half-lives of hundreds of variants in parallel.

bioRxiv · Jul 19, 2022 · PreprintBiochemistry

Deep mutational scanning of the plasminogen activator inhibitor-1 functional landscape

Z. M. Huttinger, L. M. Haynes, A. Yee, C. A. Kretz, D. R. Siemieniak, D. Ginsburg

The paper uses deep mutational scanning to assess the functional impact of amino acid substitutions in PAI-1, identifying variants that disrupt its inhibitory activity against uPA.

bioRxiv · Apr 15, 2021Biochemistry

Phage Display Broadly Identifies Inhibitor-reactive Regions in von Willebrand Factor

A. Yee, M. Dai, S. E. Croteau, J. A. Shavit, S. W. Pipe, F. Meng, D. Ginsburg

This study uses phage display and NGS to identify inhibitor-reactive regions in von Willebrand factor, revealing distinct patterns among patients and overlap with a commercial antibody.

bioRxiv · Mar 8, 2021Pathology