Author

A. Yennemadi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

G. Leisching· 2 shared J. Keane· 2 shared C. De Pasquale· 1 shared G. Jameson· 1 shared K. Gogan· 1 shared M. Bianchi· 1 shared M. Glass· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

G. Leisching

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 16, 2023

Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human monocyte-derived macrophages and blunt glycolysis in response to antigenic stimuli.

G. Leisching, A. Yennemadi, K. Gogan, J. Keane

This study examines how chronic exposure to type I interferons affects macrophage metabolism, revealing distinct metabolic profiles and functional changes in response to antigenic stimuli.

DOI 10.1101/2023.12.16.571975

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivOct 17, 2022

Chronic IFNα treatment induces leukopoiesis, increased plasma succinate and immune cell metabolic rewiring

G. Leisching, A. Yennemadi, J. Keane…·G. Jameson

This study shows that chronic IFNα treatment in rats causes hypermetabolic immune cells, increased plasma succinate, and impaired bacterial response.

DOI 10.1016/j.cellimm.2023.104741

ratproteomics

𝕏 PostBluesky