Author

A.-C. Fluckiger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:protein structure· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Diress· 3 shared B. Ontsouka· 3 shared C. Soare· 3 shared D. E. Anderson· 3 shared F. Diaz-Mitoma· 3 shared J. Bozic· 3 shared T. Ahmed· 3 shared T. Berthoud· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersImmunology

A. Diress

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3 papers

Recent·Most cited

Use of eVLP-based vaccine candidates to broaden immunity against SARS-CoV-2 variants

J. Bozic, T. Ahmed, B. Ontsouka, A.-C. Fluckiger, A. Diress, T. Berthoud, X. Yuan, L. Yang, F. Diaz-Mitoma, D. E. Anderson, C. Soare

This study evaluates eVLP-based vaccine candidates against SARS-CoV-2 variants, showing that a trivalent vaccine induces broader immunity compared to single-variant vaccines.

bioRxiv · Sep 28, 2021 · PreprintImmunology

An enveloped virus-like particle vaccine expressing a stabilized prefusion form of the SARS-CoV-2 spike protein elicits potent immunity after a single dose.

A.-C. Fluckiger, B. Ontsouka, J. Bozic, A. Diress, T. Ahmed, T. Berthoud, M. Liao, A. Tran, D. Duque, M. McCluskie, F. Diaz-Mitoma, D. E. Anderson, C. Soare

This paper evaluates an enveloped virus-like particle vaccine, VBI-2902a, which elicits strong immunity against SARS-CoV-2 after a single dose in mice and hamsters.

bioRxiv · Apr 28, 2021Immunology

ENVELOPED VIRUS-LIKE PARTICLES (eVLPs) EXPRESSING MODIFIED FORMS OF ZIKA VIRUS PROTEINS E AND NS1 PROTECT MICE FROM ZIKA VIRUS INFECTION

A.-C. Fluckiger, J. Bozic, A. Diress, B. Ontsouka, T. Ahmed, A. Ponce, M. Kirchmeier, F. Diaz-Mitoma, W. Conlan, D. E. Anderson, C. Soare

This paper develops and tests bivalent eVLP vaccines expressing modified ZIKV E and NS1 proteins, showing 100% protection in mice against ZIKV challenge.

bioRxiv · Jun 10, 2019 · PreprintImmunology