Cancer BiologybioRxiv
Genetic signature of prostate cancer resistant to optimized hK2 targeted alpha-particle therapy
M. Bicak, K. Lueckerath, T. Kalidindi…·D. Ulmert
The paper evaluates enhanced alpha-radioimmunotherapy for prostate cancer using [225Ac]hu11B6-IgG3 and analyzes genomic changes in resistant tumors.
DOI 10.1073/pnas.1918744117