Author

A. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Microbiology· 3 Animal Behavior & Cognition· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Research Focus:cell type annotation· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2

Frequent Co-Authors

A. Bui· 1 shared A. Castor· 1 shared A. D. S. Filipe· 1 shared A. Dayoub· 1 shared A. Desrichard· 1 shared A. E. Smith· 1 shared A. Gasco Hernandez· 1 shared A. Gomez· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Bui

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Selective enrichment of Methylococcaceae versus Methylocystaceae methanotrophs via control of methane feeding scheme

J. Y. Lee, M. Choi, M. J. Song, D. D. Kim, T. Yun, J. Chang, A. Ho, J. Myung, S. Yoon

This study enriches methanotrophic microbiomes from paddy soils under different methane and copper conditions, finding Methylocystis dominance and ecological importance of methanobactin in Cu-deficient environments.

bioRxiv · Mar 18, 2024 · PreprintMicrobiology

High-Throughput DNA melt measurements enable improved models of DNA folding thermodynamics

Y. Ke, E. Sharma, H. K. Wayment-Steele, W. R. Becker, A. Ho, E. Marklund, W. J. Greenleaf

This paper introduces a high-throughput method to measure DNA melting and develops models to improve DNA folding thermodynamics predictions.

bioRxiv · Jan 8, 2024Biophysics

Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV

C. Davis, I. Epifano, K. Dee, S. McFarlane, J. K. Wojtus, B. Brennan, Q. Gu, S. B. Vattipally, L. Tong, L. Orr, A. D. S. Filipe, D. A. Barr, A. Ho, E. C. Thomson, C. Boutell

This study shows that fever enhances the host's type-I IFN response to restrict MPXV replication.

bioRxiv · Sep 29, 2023 · PreprintMicrobiology

Tipifarnib potentiates the antitumor effects of PI3Kα inhibition in PIK3CA- and HRAS-dysregulated HNSCC via convergent inhibition of mTOR activity

A. E. Smith, S. Chan, Z. Wang, A. McCloskey, Q. Reilly, J. Z. Wang, H. V. Patel, K. Koshizuka, H. S. Soifer, L. Kessler, A. Dayoub, V. Villaflor, D. Adkins, J. Y. Bruce, A. Ho, , S. Malik

This study combines tipifarnib and alpelisib to target PI3K-mTOR and HRAS in HNSCC, showing synergy in mTOR inhibition and clinical potential for R/M HNSCC patients.

bioRxiv · Jan 17, 2023 · PreprintCancer Biology

Complex genotype-phenotype relationships shape the response to treatment of Down Syndrome Childhood Acute Lymphoblastic Leukaemia

C. Lutz, V. A. Turati, R. Clifford, P. S. Woll, T. Stiehl, A. Castor, S. A. Clark, H. Ferry, V. Buckle, A. Trumpp, A. Ho, A. Marciniak-Czochra, J. Herrero, A. Schuh, S. E. W. Jacobsen, T. Enver

This study investigates genotype-phenotype relationships in Down Syndrome ALL, showing that genetic and phenotypic heterogeneity influences treatment response and relapse through clonal competition.

bioRxiv · Feb 6, 2022Cancer Biology

Isolation and characterization of Streptomyces bacteriophages and Streptomyces strains encoding biosynthetic arsenals

E. T. Montano, J. F. Nideffer, L. Brumage, M. Erb, A. I. Derman, J. P. Davis, E. Estrada, S. Fu, D. Le, A. Vuppala, C. Tran, E. Luterstein, S. Lakkaraju, S. Panchagnula, C. Ren, , J. Pogliano

This study identifies novel Streptomyces strains and phages with potential for antibiotic discovery and genetic manipulation.

bioRxiv · Jun 22, 2020 · PreprintMicrobiology

Heart Rate n-Variability (HRnV) and Its Application to Risk Stratification of Chest Pain Patients in the Emergency Department

N. Liu, D. Guo, Z. X. Koh, A. Ho, F. Xie, T. Tagami, J. Sakamoto, P. P. Pek, B. Chakraborty, S. H. Lim, J. Tan, M. Ong

This study introduces HRnV, a new measure of heart rate variability, and shows it improves risk prediction for adverse cardiac events in chest pain ED patients compared to traditional scores.

bioRxiv · Feb 17, 2020Bioengineering

Pharmacological or genetic targeting of Transient Receptor Potential (TRP) channels can disrupt the planarian escape response

Z. Sabry, A. Ho, D. Ireland, C. Rabeler, O. Cochet-Escartin, E.-M. Collins

This study shows that TRP channels mediate planarian escape responses to noxious stimuli, with TRPA1 and TRPV involved in different inducers but converging on a common downstream pathway.

bioRxiv · Sep 3, 2019Animal Behavior & Cognition

Genetic signature of prostate cancer resistant to optimized hK2 targeted alpha-particle therapy

M. Bicak, K. Lueckerath, T. Kalidindi, S.-E. Strand, M. Morris, C. Radu, R. Damoiseaux, N. Peekhaus, A. Ho, D. V. Veach, A.-C. Malmborg Hager, S. M. Larson, H. Lilja, M. R. McDevitt, R. J. Klein, D. Ulmert

The paper evaluates enhanced alpha-radioimmunotherapy for prostate cancer using [225Ac]hu11B6-IgG3 and analyzes genomic changes in resistant tumors.

bioRxiv · Sep 2, 2019Cancer Biology

Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions

M. Dalin, N. Katabi, M. Persson, K.-W. Lee, V. Makarov, A. Desrichard, L. Walsh, L. West, Z. Nadeem, D. Ramaswami, J. Havel, F. Kuo, K. Chadalavada, G. Nanjangud, N. Riaz, , L. G. T. Morris

This study identifies prevalent oncogenic gene fusions in myoepithelial carcinoma through genomic analysis, highlighting TGFBR3-PLAG1 as a key fusion and potential therapeutic target.

bioRxiv · Jun 9, 2017Cancer Biology