ImmunologyScience ImmunologyPeer-reviewed
Pathogenic IgE-fated memory B cell responses retain functional plasticity
Kelly M. Bruton, Allyssa Phelps, Atai Ariaz…·Manel Jordana
This study shows that blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells from a pathogenic IgE fate to a non-pathogenic IgG2c fate.