Manel Jordana

This study shows that gut and oral bacteria metabolize peanut allergens, affecting IgE-binding and anaphylaxis severity in allergic individuals.

This study shows that blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells from a pathogenic IgE fate to a non-pathogenic IgG2c fate.

The study identifies IgE+ memory B cells in humans as rare and suggests their limited clinical utility in allergic disease.