Joshua F. E. Koenig

This study shows that gut and oral bacteria metabolize peanut allergens, affecting IgE-binding and anaphylaxis severity in allergic individuals.

This study shows that blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells from a pathogenic IgE fate to a non-pathogenic IgG2c fate.

The paper creates a searchable database of publications using fluorescent probes and flow cytometry to study antigen-specific B cells, showing increased research focus on pathogens like SARS-CoV-2 and HIV.

This study shows that type 1 immunity, via IFNγ signaling, protects intestinal tissue from damage during helminth infection without reducing parasite burden.

This paper develops an ex vivo model using murine precision-cut lung slices to study profibrotic macrophage polarization and validates its utility for fibrosis research.