Cell BiologybioRxivPreprint
Dsg2 truncation causes a lethal barrier breakdown in mice
Daniela Kugelmann, Elisabeth S. Butz, Alexander García Ponce…·Jens Waschke
This study shows that a DSG2 mutation causing Dsg2 truncation leads to a lethal intestinal barrier defect and a skewed IL17 response in mice, similar to Crohn's disease.