Alexander S. Brown

This study shows Ezh2 suppresses differentiation gene activation in cerebellar granule neurons and medulloblastoma cells, and its inhibition combined with cell cycle exit promotes differentiation.

The paper identifies Shh responsive genes and regulatory sequences involved in cochlear morphogenesis using genomic approaches.

This study identifies MTSS1/Src family kinase dysregulation as a common mechanism in multiple inherited ataxias and shows SFK inhibitors can delay disease progression in mouse models.