Cell BiologyPLoS ONEPeer-reviewed
Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechanotransduction
Mariana Moraes de Lima Perini, Alyssa F. Fayemi, Julie N. Pugh…·Jiliang Li
This study shows that primary cilia in osteoblasts and osteocytes are essential for skeletal development and mechanotransduction, as demonstrated by reduced bone growth and impaired mechanical loading response in knockout mice.