BiochemistryNature CommunicationsPeer-reviewed
DNA targeting by compact Cas9d and its resurrected ancestor
Rodrigo Fregoso Ocampo, Jack P. K. Bravo, Tyler L. Dangerfield…·David Ward Taylor
This study reports cryo-EM structures of Cas9d, revealing its DNA targeting mechanism and demonstrating a compact variant with robust nuclease activity in mammalian cells.
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