Cell BiologybioRxivPreprint
PKC Promotes T-Tubule Membrane Loss by Activating a PKD-NFκB Endocytic Pathway
Aiora Martinez-Vilchez, Ann-Katrin M. Pfeuffer, Janna Sophie Wessolowski…·Thomas Seidel
This study identifies PKC-driven T-tubule membrane loss through a PKD-NFκB endocytic pathway in cardiomyocytes, showing impaired contractility and arrhythmia risk.