Author

Anne O’Garra

Primary ORCID profile (0000-0001-9845-6134 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Anne O’GarraiD3 papers · The Francis Crick Institute

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Akul Singhania· 1 shared Andrea M. CooperiD· 1 shared Asuncion Mejias· 1 shared Aurelie A. Ray· 1 shared Catherine M. Hawrylowicz· 1 shared Charlotte Whicher· 1 shared Chloe Bloom· 1 shared Christine M Graham· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

Akul Singhania

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 24, 2019

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring

Matthew C Altman, Nicole Baldwin, Elizabeth Whalen…·Damien Chaussabel

The paper develops a targeted transcriptome fingerprinting assay using modular transcriptional repertoires to assess immune functions in clinical settings.

DOI 10.1101/587295

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 23, 2018

Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production

Leona Gabryšová, Elizabeth H. Mann, Lydia Bradley…·Anne O’Garra

This study shows that 2-deoxyglucose modulates IL-2 signaling to influence Th17 differentiation and IL-10 production by inhibiting glycosylation rather than glycolysis.

DOI 10.1101/287920

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 26, 2018

Differential expression of an alternative splice variant of IL-12Rβ1 impacts early dissemination in the mouse and associates with disease outcome in both mouse and humans exposed to tuberculosis

Mrinal K. Das, Aurelie A. Ray, Yi Cai…·Andrea M. Cooper

This study identifies an alternative splice variant of IL-12Rβ1 that limits early Mtb dissemination in mice and predicts TB disease outcomes in humans.

DOI 10.1101/271627

𝕏 PostBluesky