Anne O’Garra

The paper identifies immune signatures in TB contacts that predict protection or progression to active TB using single-cell RNA sequencing and correlates findings with non-human primate data.

This study identifies a hyper-inflammatory immune response in HIV-associated TB meningitis, marked by cytotoxic CD8 T cells, activated neutrophils, and type 1 interferon signaling.

This study shows Blimp-1 and c-Maf regulate gene networks in T cells to prevent colitis, with distinct roles in controlling inflammatory pathways in mouse models.