NIX-associated mitochondrial remodeling contributes to esophageal epithelial differentiation
No’ad Shanas, Aissata Balde, Annie D. Fuller, Jazmyne L. Jackson, Anne Staub, John M. Crespo, William Nazario-Lugo, Alexander Tufano, Nicholas M. McDonald, Andres Klein Szanto, Kathy Qi Cai, Melanie A. Ruffner, Amanda B. Muir, Zachary Reichenbach, Kelly A. Whelan
This study shows that NIX-mediated mitochondrial remodeling is essential for esophageal epithelial differentiation and that its disruption may contribute to eosinophilic esophagitis.
bioRxiv · Sep 18, 2026 · PreprintCell Biology