Pharmacology & ToxicologybioRxivPreprint
Discovery of a functionally selective serotonin 5-HT1A receptor agonist for the treatment of pain
Annika Ullrich, Johannes Schneider, João M. Braz…·Peter Gmeiner
The paper identifies ST171, a selective 5-HT1A receptor agonist effective in pain models without sedation, and elucidates its mechanism through structural and computational analysis.
DOI 10.1101/2023.09.11.557127