NeurosciencebioRxivPreprint
NDR1/2 kinases regulate membrane trafficking, enable efficient autophagy and prevent neurodegeneration
Flavia Roşianu, Simeon R. Mihaylov, Noreen Eder…·Sila K. Ultanir
This study shows that dual loss of NDR1/2 kinases in neurons causes neurodegeneration, disrupts endocytosis, and impairs autophagy by affecting membrane trafficking and protein homeostasis.
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