Cell BiologybioRxivPreprint
β-Catenin tumour-suppressor activity depends on its ability to promote Pro-N-Cadherin maturation
Antonio Herrera, Anghara Menendez, Blanca Torroba, Sebastian Pons
This study shows that β-Catenin promotes Pro-N-Cadherin maturation, which is necessary for apical junction formation and apico-basal polarity, and that this activity suppresses tumor formation in neural stem cells.
DOI 10.1101/571810