Author

Arun M. Unni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Harold Varmus· 2 shared Antonino MontalbanoiD· 1 shared Bryant Harbourne· 1 shared Eric E. GardneriD· 1 shared Jerin Thomas· 1 shared John BlenisiD· 1 shared John R. Ferrarone· 1 shared Kate Li· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Harold Varmus

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 19, 2023

LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase

John R. Ferrarone, Jerin Thomas, Arun M. Unni…·Harold Varmus

This study identifies LKB1's role in suppressing growth by activating PIKFYVE to promote EGFR internalization in LUAD.

DOI 10.1101/2023.10.19.563158

humangenetic perturbation / CRISPR

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 21, 2017

Hyperactivation of extracellular signal-regulated kinase (ERK) by RAS-mediated signaling or inhibition of dual specificity phosphatase 6 (DUSP6) is associated with toxicity in lung adenocarcinoma cells with mutations in KRAS or EGFR

Arun M. Unni, Bryant Harbourne, Min Hee Oh…·Harold Varmus

The paper identifies ERK hyperactivation via RAS signaling or DUSP6 inhibition as toxic in KRAS or EGFR mutant lung adenocarcinoma cells, suggesting therapeutic strategies targeting feedback regulators.

DOI 10.1101/222505

humanexperimental assay

𝕏 PostBluesky