PhysiologyJCI InsightPeer-reviewed
Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles.
Shinobu Miyazaki‐Anzai, Masashi Masuda, Audrey L. Keenan…·Makoto Miyazaki
This study shows that activating the IKK2-NFκB pathway in vascular smooth muscle cells reduces calcifying extracellular vesicles, thereby decreasing vascular stiffness in CKD.
16 citations