NeurosciencebioRxivPreprint
Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid beta aggregates in vivo in a mouse model of Alzheimer's disease
María Calvo-Rodríguez, Elizabeth K. Kharitonova, Austin C. Snyder…·Brian J. Bacskai
The paper uses real-time imaging to show increased mitochondrial oxidative stress in neurons near Aβ plaques in a mouse model of Alzheimer's disease, and demonstrates that this stress can be reduced by targeting calcium influx or using antioxidants.