Cancer BiologybioRxiv
Sustained Androgen Receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis
M. Ma, S. Ghosh, D. Tavernari…·G.-P. Dotto
This study shows that androgen receptor signaling promotes melanoma cell growth and tumorigenesis, with AR inhibition reducing proliferation, enhancing DNA repair, and inducing immune responses.
DOI 10.1084/jem.20201137