Author

B. Arun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Gutierrez· 1 shared A. M. Gutierrez· 1 shared A. Paulucci-Holthauzen· 1 shared B. Gracia· 1 shared E. Irajizad· 1 shared F. C. Hsiao· 1 shared G. I. Karras· 1 shared H. Katayama· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Gutierrez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

J. Vykoukal, Y. Chen, M. J. Hong, M. Zuo, H. Krishna, H. Katayama, E. Irajizad, R. Wu, R. Leon-Letelier, J. B. Dennison, A. Gutierrez, A. Paulucci-Holthauzen, T. C. Thompson, L. Rusling, Y. Cai, , J. F. Fahrmann

The paper identifies a metabolic vulnerability in triple-negative breast cancer through sphingolipid metabolism, showing that targeting this pathway with eliglustat reduces tumor growth and improves survival.

bioRxiv · Apr 4, 2024 · PreprintCancer Biology

Protein-Folding Chaperones Predict Structure-Function Relationships and Cancer Risk in BRCA1 Mutation Carriers

B. Gracia, P. Montes, A. M. Gutierrez, B. Arun, G. I. Karras

This study uses chaperone interactions to predict pathogenicity and cancer risk in BRCA1 mutation carriers by assessing structural and phenotypic defects.

bioRxiv · Sep 14, 2023 · PreprintBiochemistry