Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques
W. B. Williams, R. Meyerhoff, R. J. Edwards, H. Li, N. Nicely, R. Henderson, Y. Zhou, K. Janowska, K. Mansouri, K. Manne, V. Stalls, A. L. Hsu, M. J. Borgnia, G. Stewart-Jones, M. S. Lee, , B. F. Haynes
The paper identifies Fab-dimerized glycan-reactive antibodies in HIV-infected macaques and HIV-naïve humans that neutralize HIV-1 and can be elicited by vaccination.
bioRxiv · Jun 30, 2020 · PreprintImmunology