Disruption of NOX2-dependent Oxidative Injury with a Targeted Gene-Therapy Approach Prevents Atrial Fibrillation in a Canine Model
S. Yoo, A. Pfenniger, J. Hoffman, W. Zhang, J. Ng, A. Burrell, D. A. Johnson, G. Gussak, T. Waugh, S. Bull, B. Benefield, B. P. Knight, R. Passman, J. A. Wasserstrom, G. L. Aistrup, R. Arora
This study shows that disrupting NOX2-dependent oxidative injury with gene therapy prevents atrial fibrillation in dogs.
bioRxiv · Sep 11, 2019 · PreprintPhysiology