Regions of Highly Recurrent Electrogram Morphology at Sites of Low Cycle Length Accurately Reflect Arrhythmogenic Substrate for Atrial Fibrillation - Implications For a New, Mechanism Guided Therapeutic Approach for Atrial Fibrillation
S. Yoo, M. Rottmann, J. Ng, D. A. Johnson, B. M. Shanab, A. Pfenniger, G. E. Geist, S. Mandava, A. Burrell, W. Zhang, J. A. Wasserstrom, B. P. Knight, R. Passman, J. Goldberger, R. Arora
This study identifies electrogram morphology recurrence as a marker of arrhythmogenic substrate in atrial fibrillation, suggesting it could guide targeted ablation therapy.
bioRxiv · Dec 10, 2020 · PreprintPhysiology