Author

B. Bhatt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

G. K. Lohia· 2 shared K. N. Balaji· 2 shared P. Prakhar· 2 shared R. S. Rajmani· 2 shared A. Peier· 1 shared A. Sadruddin· 1 shared A. Stoeck· 1 shared A. W. Partridge· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

G. K. Lohia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling

S. Lim, N. Boyer, N. Boo, C. Huang, G. Venkatachalam, Y.-C. A. Juang, M. Garrigou, K. Kaan, K. M. Peh, A. Sadruddin, P. Gopal, R. Duggal, T. Y. Yuen, S. Ng, S. Kannan, , A. W. Partridge

This paper identifies macrocyclic peptides that inhibit KRAS signaling by binding to its hydrophobic pocket, showing on-target activity and improved proteolytic stability.

bioRxiv · Sep 11, 2021Biochemistry

Preexisting mycobacterial infection modulates Candida albicans-driven pyroptosis

B. Bhatt, P. Prakhar, G. K. Lohia, R. S. Rajmani, K. N. Balaji

This study shows that preexisting Mtb infection promotes C. albicans survival by modulating macrophage pyroptosis through COP1-mediated IRF9 degradation, leading to increased fungal burden and host mortality.

bioRxiv · Aug 4, 2021Microbiology

G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

P. Prakhar, B. Bhatt, T. Mukherjee, G. K. Lohia, U. Kolthur-Seetharam, N. R. Sundaresan, R. S. Rajmani, K. N. Balaji

This study identifies G9a and Sirt6 as epigenetic regulators that modulate host cholesterol accumulation, supporting Mycobacterium tuberculosis survival.

bioRxiv · Feb 27, 2021Microbiology