MicrobiologybioRxiv
Preexisting mycobacterial infection modulates Candida albicans-driven pyroptosis
B. Bhatt, P. Prakhar, G. K. Lohia…·K. N. Balaji
This study shows that preexisting Mtb infection promotes C. albicans survival by modulating macrophage pyroptosis through COP1-mediated IRF9 degradation, leading to increased fungal burden and host mortality.
DOI 10.1111/febs.16243