B. Chan

Evaluating Synergy of Clinically Utilized Phage OMKO1 with Five Antibiotics from Different Classes against Pseudomonas aeruginosa

This study evaluates the synergy between phage OMKO1 and five antibiotics against Pseudomonas aeruginosa, showing reduced MIC and resistant regrowth in four of five combinations.

Activity-driven chromatin organization during interphase: compaction, segregation, and entanglement suppression

This paper develops a theory and validates it with simulations showing that active loop extrusion by cohesin causes chromatin compaction, TAD segregation, and suppression of entanglements during interphase.

The genome of Litomosoides sigmodontis illuminates the origins of Y chromosomes in filarial nematodes

This study generates a chromosome-level genome of Litomosoides sigmodontis and shows that filarial Y chromosomes originated from unfused autosomes through X-autosome fusions, not from a neo-Y-linked sex-determining locus.

Realtime morphological characterization and sorting of unlabeled viable cells using deep learning

COSMOS enables real-time, unlabeled cell sorting based on morphology using deep learning, achieving high enrichment of viable cells for functional analysis.

Rapid screening of pest resistance genes in maize using a sugarcane mosaic virus vector

This study uses a sugarcane mosaic virus vector to rapidly test the efficacy of various transgenes against maize pests, finding reduced larval growth in most cases.